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Pathophysiology of Varicella

Varicella is caused by the varicella-zoster virus. The disease is generally regarded as a mild, self-limiting viral illness with occasional complications. Varicella is common and highly contagious and affects nearly all susceptible children before adolescence. Although most varicella infection confers life-long immunity, varicella clinical reinfections among healthy children have been described. Varicella, commonly known in the United States as chickenpox. Chickenpox is usually a benign disease in children, and almost all children recover uneventfully. However, varicella is not totally benign even today. A significant number of varicella cases are associated with complications, among the most serious of which are varicella pneumonia and encephalitis. The virus enters the body through the mucosa of the upper respiratory tract / oropharynx that is the virus passes from one person to another through saliva sparks coming from coughing / sneezing patients and flown through the air and direc...

Varicella Clinical Manifestations

Varicella is a highly contagious infection caused by the varicella-zoster virus, which is a member of the herpes group of viruses. It is usually a mild disease that lasts a short time in healthy children. However, it can be severe in adults and may cause serious and even fatal complications in people of any age. Complications of the disease include: infection of the lesions; pneumonia (lung infection); difficulty walking and balancing; meningitis (infection of the membrane around the brain and spinal cord); and encephalitis (brain infection). Varicella Clinical Manifestations The incubation period of Varicella takes about 8-12 days. Clinical symptoms began with symptom prodormal that is not very high fever, fast feel weak, tired, lethargic, no appetite, headache, occasional abdominal pain, back pain, and anorexia. Then followed the emergence of skin eruption of erythematous papules that within a few hours turned into a vesicle. These vesicles form a typical form of droplets emben (tear...