Pathophysiology of Varicella
Varicella is caused by the varicella-zoster virus. The disease is generally regarded as a mild, self-limiting viral illness with occasional complications. Varicella is common and highly contagious and affects nearly all susceptible children before adolescence. Although most varicella infection confers life-long immunity, varicella clinical reinfections among healthy children have been described. Varicella, commonly known in the United States as chickenpox. Chickenpox is usually a benign disease in children, and almost all children recover uneventfully. However, varicella is not totally benign even today. A significant number of varicella cases are associated with complications, among the most serious of which are varicella pneumonia and encephalitis. The virus enters the body through the mucosa of the upper respiratory tract / oropharynx that is the virus passes from one person to another through saliva sparks coming from coughing / sneezing patients and flown through the air and direc...