Mitral Stenosis and Myocardial Infarction

Myocardial Infarction - Mitral Stenosis


Mitral stenosis

Mitral stenosis is a valvular heart disease characterized by the narrowing of the orifice of the mitral valve of the heart.

Symptoms of mitral stenosis include:

  • Heart failure symptoms, such as dyspnea on exertion, orthopnea and paroxysmal nocturnal dyspnea (PND)
  • Palpitations
  • Chest pain
  • Hemoptysis
  • Thromboembolism in later stages when the left atrial volume is increased (i.e., dilation). The latter leads to increase risk of atrial fibrillation, which increases the risk of blood stasis (motionless). This increases the risk of coagulation.
  • Ascites and edema and hepatomegaly (if right-side heart failure develops)
  • Fatigue and weakness increase with exercise and pregnancy.

Myocardial Infarction

Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, is the interruption of blood supply to a part of the heart, causing heart cells to die. This is most commonly due to occlusion (blockage) of a coronary artery following the rupture of a vulnerable atherosclerotic plaque, which is an unstable collection of lipids (fatty acids) and white blood cells (especially macrophages) in the wall of an artery. The resulting ischemia (restriction in blood supply) and oxygen shortage, if left untreated for a sufficient period of time, can cause damage or death (infarction) of heart muscle tissue (myocardium).


Signs and symptoms

Patients with typical myocardial infarction may have the following prodromal symptoms in the days preceding the event (although typical STEMI may occur suddenly, without warning):
  • Fatigue
  • Chest discomfort
  • Malaise
Typical chest pain in acute myocardial infarction has the following characteristics:
  • Intense and unremitting for 30-60 minutes
  • Retrosternal and often radiates up to the neck, shoulder, and jaw and down to the ulnar aspect of the left arm
  • Usually described as a substernal pressure sensation that also may be characterized as squeezing, aching, burning, or even sharp
  • In some patients, the symptom is epigastric, with a feeling of indigestion or of fullness and gas
The patient’s vital signs may demonstrate the following in myocardial infarction:
  • The patient’s heart rate is often increased secondary to sympathoadrenal discharge
  • The pulse may be irregular because of ventricular ectopy, an accelerated idioventricular rhythm, ventricular tachycardia, atrial fibrillation or flutter, or other supraventricular arrhythmias; bradyarrhythmias may be present
  • In general, the patient's blood pressure is initially elevated because of peripheral arterial vasoconstriction resulting from an adrenergic response to pain and ventricular dysfunction
  • However, with right ventricular myocardial infarction or severe left ventricular dysfunction, hypotension is seen
  • The respiratory rate may be increased in response to pulmonary congestion or anxiety
  • Coughing, wheezing, and the production of frothy sputum may occur
  • Fever is usually present within 24-48 hours, with the temperature curve generally parallel to the time course of elevations of creatine kinase (CK) levels in the blood. Body temperature may occasionally exceed 102°F

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